Oxidative reactions of azines. 2.* Synthesis and molecular structure of 3, 4-dihydroxy-1-methyl-2-oxo-4-(γ-pyridyl) piperidine

…, AT Soldatenkov, AI Stash, NY Chernikova…

文献索引：Bekro; Soldatenkov; Stash; Chernikova; Chernyshev Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 10 p. 1178 - 1181

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被引用次数: 7

摘要

A previous report [1] has identified a novel regioselective oxidation of 1,2,3,6-tetrahydr~,yridines having a phenyl group in the 4 position. In this work we have studied the oxidation of the tetrahydropyridine I which has a 3,-pyridyl substituent at C 4. Through its conjugation with the allylamine part of the piperidine ring, this heteroaromatic r-defuzient substituent can affect the reactivity in two ways. Firstly, it can activate oxidation of the C 7 methyle~ group to a ketone and secondly ...