前往化源商城

4-Hydroxy-2-quinolones. 30 Alkylation of 1H-2-oxo-3-carbethoxy-4-hydroxyquinoline

…, OV Gorokhova, IV Gorlacheva, PA Bezuglyi…

文献索引:Ukrainets; Taran; Gorokhova; Gorlacheva; Bezuglyi; Turov Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 8 p. 952 - 959

全文:HTML全文

被引用次数: 5

摘要

The ethyl esters of 1-alkyl-substituted 2-oxo-4-hydroxyquinoline-3-carboxylic acids are of interest as a starting point in the synthesis of compounds with high levels of activity as antithyroid preparations [2, 3], local anesthetics [4], anti- inflammatory agents [5-7], antimicrobial preparations [8], and other types of pharmaceuticals. The methods that are known for obtaining these compounds [7, 9, 10] are based on the use of esters of N-alkylanthranilic acids as the starting ...