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Russian Journal of General Chemistry

Basic techniques of working on a solid phase: From ABC of the peptide synthesis to libraries of non-natural amino acids

EV Babaev, DS Ermolat'ev

文献索引:Babaev; Ermolat'ev Russian Journal of General Chemistry, 2010 , vol. 80, # 12 p. 2572 - 2589

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被引用次数: 2

摘要

Abstract Libraries of hardly available amino acids bearing a heteroaromatic ring (2- pyrimidyl, substituted 2-pyridyl or 2-thiazolyl) at the amino group were prepared using solid- phase synthesis on various resins. The synthesized compounds are structurally similar to some known antidiabetic drugs. The paper combines features of a review (elementary introduction to the solid-phase synthesis methodology and technique for beginners and ...