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4′′-Benzoylureido-TSAO Derivatives as Potent and Selective Non-Nucleoside HCMV Inhibitors. Structure− Activity Relationship and Mechanism of Antiviral Action

S de Castro, MT Peromingo, L Naesens…

文献索引:Shimizu, Nobuhiro; Mori, Naoki; Kuwahara, Yasumasa Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 8 p. 1732 - 1736

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被引用次数: 14

摘要

... Volume: Page: ... 8(16) was reacted with TDSCl/DMAP at 100 °C in dry acetonitrile to give compound 9 (50% yield), which was treated with ... Finally, the 4-benzoylureido-sultone 33 was prepared in 67% yield as shown in Scheme 5. Thus, treatment of the ketone ...