Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction

…, KS Pillinger, W Li, AE Taylor, AE Graham

文献索引：Phillips, David J.; Pillinger, Kathryn S.; Li, Wei; Taylor, Angela E.; Graham, Andrew E. Chemical Communications, 2006 , # 21 p. 2280 - 2282

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被引用次数: 13

摘要

Diols are desymmetrized by a tandem oxidation/Wittig olefination to give α, β-unsaturated hydroxy esters without the requirement for protecting group strategies; the α, β-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.