Tetrahedron

Asymmetric reductions of (trifluoroacetyl) biphenyl derivatives with bakers' yeast and with Geotrichum candidum acetone powder

T Fujisawa, Y Onogawa, A Sato, T Mitsuya, M Shimizu

文献索引：Fujisawa, Tamotsu; Onogawa, Yoshio; Sato, Akira; Mitsuya, Takeshi; Shimizu, Makoto Tetrahedron, 1998 , vol. 54, # 17 p. 4267 - 4276

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被引用次数: 31

摘要

The bakers' yeast reduction of (trifluoroacetyl) biphenyl derivatives produces (R)- trifluoromethyl biphenylyl carbinols in high enantioselectivity, whereas the reduction of the same derivatives with Geotrichum candidum acetone powder gives the corresponding (S)- carbinols in excellent yields and enantioselectivity.