Discovery of pyrrolopyridine− pyridone based inhibitors of Met kinase: Synthesis, X-ray crystallographic analysis, and biological activities

…, C Darienzo, A Kamath, P Marathe…

文献索引：Thibault, Carl; L'Heureux, Alexandre; Bhide, Rajeev S.; Ruel, Rejean Organic Letters, 2003 , vol. 5, # 26 p. 5023 - 5025

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被引用次数: 73

摘要

... Volume: Page: ... to the literature procedure,(11) was reacted with triazine 25 to obtain ester 26.(12) Ester 26 was hydrolyzed ... N-hydroxyethyl substituted 4-pyridone analogues 34 and 37 were obtained from intermediate 3-bromo-4-hydroxypyrine-5-carboxylic acid ...