Structure-activity relationships of 1, 2, 4-benzotriazine 1, 4-dioxides as hypoxia-selective analogues of tirapazamine

MP Hay, SA Gamage, MS Kovacs…

文献索引：Shigyo; Sato; Shibuya; Takahashi; Yamaguchi; Sonoki; Ohta Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 9 p. 1573 - 1582

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被引用次数: 89

摘要

... 10.1021/jm020367+. Publication Date (Web): December 2, 2002. Copyright © 2003 American Chemical Society. ... partition coefficients at pH 7.4 were determined by a low volume shake flask ... to “train” ACD LogP prediction software (v. 4.5, Advanced Chemistry Development Inc ...