Tetrahedron letters

A highly efficient practical method for the synthesis of chiral polyhydroxy-(E, E)-1-chlorodienols and (E)-5-hydroxy enynes

JS Yadav, DK Barma, D Dutta

文献索引：Yadav; Barma; Dutta, Dinah Tetrahedron Letters, 1997 , vol. 38, # 25 p. 4479 - 4482

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被引用次数: 9

摘要

An efficient protocol for the synthesis of chiral polyhydroxy-(E, E)-1-chlorodienols and (E)-5- hydroxy enynes from chiral 4, 5-epoxy trans allyl chlorides and 4, 5-O-isopropylidene allyl chlorides is described by using stoichiometric amount of LiNH2 or LDA in HMPA: THF (1: 5) useful in the synthesis of biologically active natural products.