Synthesis and Acidity of 5-Phenyltetrazol-2-ylalkanoic Acids and the Corresponding 5-(5-Phenyltetrazol-2-ylalkyl) tetrazoles

KA Esikov, VY Zubarev, EV Bezklubnaya…

文献索引：Esikov; Zubarev; Bezklubnaya; Malin; Ostrovskii Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 8 p. 986 - 991

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被引用次数: 1

摘要

Abstract We have obtained 5-phenyltetrazol-2-ylalkanoic acids and their derivatives containing terminal nitrile, amide, and tetrazol-5-yl groups. Tetrazolylalkanoic acids with two (p K a 4.93) and three (p K a 5.45) bridging methylene groups are weaker acids than the corresponding ditetrazoles p K a 4.68 and 5.29 respectively). However, the acidity of 5- phenyltetrazol-2-ylacetic acid (p K a 3.12), is higher than acidity of the corresponding ...