Resolution of amino acids. XII. Preparation of L-2-amino-5-arylpentanoic acids, constituent amino acids in AM-toxins.

Y Shimohigashi, S Lee, N Izumiya

文献索引：Shimohigashi,Y. et al. Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 3280 - 3284

全文：HTML全文

被引用次数: 36

摘要

The L-forms of 2-amino-5-(p-methoxyphenyl) pentanoic acid (Amp), 2-amino-5- phenylpentanoic acid (App), and 2-amino-5-(p-hydroxyphenyl) pentanoic acid (Ahp) are constituent amino acids in AM-toxins. The O-methyl linkage of L-Amp was hydrolyzed gradually by heating with hydrochloric acid. A procedure without drastic acid treatment is given for the synthesis and resolution of Amp. Diethyl [3-(p-methoxyphenyl) propyl] ...