Synthesis of 5??substituted 2??oxazolidinethiones and their antagonism to uterotropic effect of diethylstilbestrol

…, SS Parmar, C Dwivedi, RD Harbison

文献索引：Agrawal; Parmar; Dwivedi; Harbison Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 6 p. 887 - 889

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被引用次数: 1

摘要

Abstract 5-(4-Aminophenoxymethyl)-2-oxazolidinethiones were synthesized by the cyclization of 1-(4-aminophenoxy)-3-amino-2-propanol in the presence of potassium hydroxide and carbon disulfide. This oxazolidinethione, on reaction with suitable isothiocyanates, yielded 5-[4-(substituted thiocarbamido) phenoxymethyl]-2- oxazolidinethiones. These compounds antagonized the uterotropic effects of ...