Amine Activation: Synthesis of N-(Hetero) arylamides from Isothioureas and Carboxylic Acids

YP Zhu, S Sergeyev, P Franck, RVA Orru…

文献索引：Schaefer, Gabriel; Bode, Jeffrey W. Organic Letters, 2014 , vol. 16, # 5 p. 1526 - 1529

全文：HTML全文

被引用次数: 1

摘要

... Organic Letters. Advanced Search. ... The synthesis of the amide functional group is paramount in organic chemistry ... When N-tert-butyl-S,N′-diphenylisothiourea (1d) was used instead of 1a, full conversion could be achieved with only 2.5 mol % catalyst, and the desired product 4a ...