Tetrahedron letters

A concise and stereoselective synthesis of (+)-and (−)-deoxoprosophylline

SP Chavan, C Praveen

文献索引：Chavan, Subhash P.; Praveen, Cherukupally Tetrahedron Letters, 2004 , vol. 45, # 2 p. 421 - 423

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被引用次数: 35

摘要

Although many elegant synthesis of (+)- and (−)-deoxoprosophylline have been documented in the literature, 5 most of the syntheses use chiral pool starting materials such as sugars, amino acids and involve many steps. Due to their interesting structural features and the biological significance of this class of compounds, we were encouraged to design a short and effective synthesis of (+)- and (−)-deoxoprosophylline, using Sharpless asymmetric dihydroxylation as the ...