Organic letters

Boron trifluoride-mediated alkylation of diphenylphosphine with tert-alkyl fluoride

K Hirano, H Yorimitsu, K Oshima

文献索引：Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro Organic Letters, 2004 , vol. 6, # 26 p. 4873 - 4875

被引用次数: 26

摘要

Treatment of tertiary alkyl fluoride with diphenylphosphine in the presence of a stoichiometric amount of boron trifluoride etherate yields the corresponding tert- alkyldiphenylphosphine despite the coexistence of the strong Lewis acid and the highly coordinating phosphine. Use of diphenyl (trimethylsilyl) phosphine as a nucleophile makes the reaction catalytic in boron trifluoride.