Preparation of β-and γ-lactams from carbamoyl radicals derived from oxime oxalate amides

EM Scanlan, AMZ Slawin, JC Walton

文献索引：Scanlan, Eoin M.; Slawin, Alexandra M.Z.; Walton, John C. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 5 p. 716 - 724

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被引用次数: 30

摘要

A general synthetic route to oxime oxalate amides was developed and applied to the preparation of molecules incorporating N-benzyl-N-alkenyl amides linked with acetone oxime or benzaldoxime units. In addition, 2-substituted-thiazolidine-4-carboxylic acid methyl ester amides of oxalyl benzaldoxime were also prepared. It was shown by EPR spectroscopy that the oxalyl benzaldoxime amides dissociated to produce benziminyl and ...