Water??Soluble Chiral Ruthenium (II) Phenyloxazoline Complex: Reusable and Highly Enantioselective Catalyst for Intramolecular Cyclopropanation Reactions

AM Abu??Elfotoh, DPT Nguyen…

文献索引：Abu-Elfotoh, Abdel-Moneim; Nguyen, Diem Phuong Thi; Chanthamath, Soda; Phomkeona, Kesiny; Shibatomi, Kazutaka; Iwasa, Seiji Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3435 - 3439

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被引用次数: 13

摘要

Abstract The intramolecular cyclopropanation of various trans-allylic diazoacetates and alkenyl diazoketones has been achieved with excellent enantioselectivities of up to 98% ee and in quantitative yields by using a water-soluble ruthenium (II)/hydroxymethyl (phenyl) oxazoline catalyst in a water/ether biphasic medium. The catalyst could be reused at least five times.