Tetrahedron: Asymmetry

Enzymatic resolution of cyclic N-Boc protected β-aminoacids

…, R Callens, M Haddad, M Larchevêque

文献索引：Pousset, Cyrille; Callens, Roland; Haddad, Mansour; Larcheveque, Marc Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3407 - 3412

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被引用次数: 19

摘要

Methyl and ethyl esters of N-Boc homoproline, homopipecolic acid and 3-carboxymethyl- morpholine were kinetically resolved by hydrolysis catalysed by Burkholderia cepacia lipase to give the corresponding acids and residual esters in enantiomeric excesses better than 99%(E> 100).