Abstract Efficient enantioselective synthetic methods for (R)-α-alkylhomoserines and (R)-α- alkylhomocysteines have been developed. The phase-transfer catalytic alkylation of 2- phenyl-5, 6-dihydro-4H-1, 3-oxazine-4-carboxylic acid tert-butyl ester and 2-phenyl-5, 6- dihydro-4H-1, 3-thiazine-4-carboxylic acid tert-butyl ester, in the presence of N-2′, 3′, 4′- trifluorobenzylcinchonidinium bromide, gave the corresponding alkylated products, which ...
