Tetrahedron Letters

Solid-phase cross-coupling reaction of aryl (fluoro) silanes with 4-iodobenzoic acid

F Homsi, K Nozaki, T Hiyama

文献索引：Homsi, Fadi; Nozaki, Kyoko; Hiyama, Tamejiro Tetrahedron Letters, 2000 , vol. 41, # 31 p. 5869 - 5872

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被引用次数: 18

摘要

The palladium-catalyzed cross-coupling reaction of aryl(difluoro)silanes with iodoarenes has been shown to give good to high yields of unsymmetrical biaryls. 7 Our research goal was to transfer this reaction from solution phase to solid phase and identify a general set of conditions that allow complete conversion to products from a wide range of substrates (Scheme 1). ... Initially, we synthesized compounds 2a,b,g as the representative silanes 7 a and used 2a ...