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Synthesis of proline analogues as potent and selective cathepsin S inhibitors

M Kim, J Jeon, J Song, KH Suh, YH Kim, KH Min…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 11 p. 3140 - 3144

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被引用次数: 7

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... We found a cathepsin S inhibitor, compound 4, with an IC 50 value of 156 nM through screening of our in-house, proline-based focused chemical library. ...