Abstract Treatment of 9-(RS)-(2, 3-dihydroxypropyl) adenine (III) with bromine in water afforded the 8-bromo derivative IV which on reaction with acetone was converted into the 1, 3-dioxolane derivative VI. Reaction of compound VI with 1, 3-diaminopropane, followed by acid hydrolysis, gave 9-(RS)-(2, 3-dihydroxypropyl)-8-(3-aminopropylamino) adenine (VIII). Compound IV reacts with 1, 3-diaminopropane under formation of a mixture of compound ...