Acetylquinolines and acetylisoquinolines were obtained from the corresponding chloro-, bromo-or trifluoromethylsulfonyloxy-heteroaromatics via four different palladium-catalyzed coupling reactions:(i) Stille coupling with tri (n-butyl)-1-ethoxyvinylstannane;(ii) Negishi coupling with 1-ethoxyvinylzinc chloride;(iii) cross-coupling with tri (1-ethoxyvinyl) indium;(iv) Heck arylation of n-butyl vinyl ether.
