Chemical Communications

Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H 2 catalyzed by ruthenium pincer complexes

D Srimani, Y Ben-David, D Milstein

文献索引：Srimani, Dipankar; Ben-David, Yehoshoa; Milstein, David Chemical Communications, 2013 , vol. 49, # 59 p. 6632 - 6634

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被引用次数: 46

摘要

A novel, one-step synthesis of substituted pyridine-and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C–N and C–C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.