5-Phenyl-2-(2-propynylarnino)-2-oxazolin-4-one and derivatives were synthesized by heating 2-amino-5-phenyl-2-oxazolin-4-one and its derivatives with 2-propynylamine in ethanol. 2-[(l, l-Dialkyl-2-propynyl)-amino]-5-phenyl-2-oxazolin-4-ones were obtained by cyclization of 1-(a-chlorophenylacetyl)-3-(1, l-dialkyl-2-propyny1) ureas with sodium ethoxide in ethanol. These compounds were evaluated for antidepressant activity by the ...