Organic letters

The palladium (II)-catalyzed Nazarov reaction

C Bee, E Leclerc, MA Tius

文献索引：Bee, Cisco; Leclerc, Eric; Tius, Marcus A. Organic Letters, 2003 , vol. 5, # 26 p. 4927 - 4930

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被引用次数: 75

摘要

The PdCl 2 -catalyzed cyclization of α-alkoxy dienones leads to 2-hydroxycyclopentenones, whereas the Pd(OAc) 2 -catalyzed reaction leads to cross-conjugated cyclopentenones through an oxidative process. ... During the course of a survey of Lewis acids for use in a catalytic asymmetric version 1 of the Nazarov reaction, 2 we examined the effect of PdCl 2 (MeCN) 2 on dienone 1a. Cyclization to 2-hydroxycyclopentenone 2a took place in 91% yield in the presence of ...