Synthesis of [11C] N??(2??chloro??5??thiomethylphenyl)??N′??(3??methoxyphenyl)??N′??methylguanidine ([11C] GMOM): a candidate PET tracer for imaging the PCP site …
RN Waterhouse, F Dumont, A Sultana…
文献索引：Waterhouse, Rikki N.; Dumont, Filip; Sultana, Abida; Simpson, Norman; Laruelle, Marc Journal of Labelled Compounds and Radiopharmaceuticals, 2002 , vol. 45, # 11 p. 955 - 964
Abstract The N-methyl-D-aspartate (NMDA) ion channel plays an important role in a number of neurodegenerative disorders including stroke, Parkinson's disease, Huntington's Chorea, Alzheimer's disease, schizophrenia and epilepsy. To provide effective radioligands for imaging the PCP binding site of the NMDA ion channel, we synthesized and characterized in vitro the candidate PCP site ligand N-(2-chloro-5-thiomethylphenyl)-N′-(3- ...
