Reactions of dianions with nitriles. A new pyridine synthesis

RB Bates, B Gordon III, PC Keller…

文献索引：Bates, Robert B.; Gordon, Bernard; Keller, Philip C.; Rund, John V.; Mills, Nancy S., Journal of Organic Chemistry, 1980 , vol. 45, # 1 p. 168 - 169

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被引用次数: 32

摘要

29 a See Experimental Section for details. to 0" C under a nitrogen atmosphere was added 7.4 mL (26.0 mmol) of Vitride12 (3.5 11 solution of sodium bis (2-methoxyethoxy) aluminum hydride in benzene). The resulting dark solution was stirred at 0" C for 30 min and brought to- 78" C. 2-Butanol (2.3 mL, 26.0 mmol) was cautiously introduced via syringe, followed by a solution of the ene nitrile (1.3 mmol) in dry tetrahydrofuran (5 mL). After 2 h at this ...