Chinese Chemical Letters

Synthesis of 2, 5-disubstitued benzimidazole using SnCl 2-catalyzed reduction system at room temperature

LP Duan, Q Li, NB Wu, DF Xu, HB Zhang

文献索引：Duan, Li-Ping; Li, Qiang; Wu, Ning-Bo; Xu, Dong-Fang; Zhang, Hao-Bing Chinese Chemical Letters, 2014 , vol. 25, # 1 p. 155 - 158

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被引用次数: 5

摘要

Abstract Stannous chloride dihydrate is used as an efficient catalyst in reductive cyclization of 2-nitro-5-substituted aniline Schiff base leading to stable 2, 5-disubstitued benzimidazole derivatives in excellent yields with good purity. It provides a novel method of synthesis of 2, 5- disubstitued benzimidazole under reductive system at room temperature.