Tetrahedron

Alternative method for the reduction of aromatic nitro to amine using TMDS-iron catalyst system

…, W Dayoub, P Demonchaux, G Mignani, M Lemaire

文献索引：Pehlivan, Leyla; Metay, Estelle; Laval, Stephane; Dayoub, Wissam; Demonchaux, Patrice; Mignani, Gerard; Lemaire, Marc Tetrahedron, 2011 , vol. 67, # 10 p. 1971 - 1976

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被引用次数: 51

摘要

The system 1, 1, 3, 3-tetramethyldisiloxane (TMDS)/Fe (acac) 3 is reported here as a new method to obtain amines from aromatic nitro compounds. Amines are synthetized in a straightforward step and are isolated as hydrochloride salts with good to excellent yields. This system has shown a good selectivity toward aryl-chloride, aryl-bromide, ester, carboxylic acid, and cyano groups. The reduction of alkylnitro compounds was ...