Rapid one-pot synthesis of alkane-α, ω-diylbisphosphonic acids from dihalogenoalkanes under microwave irradiation

D Villemin, B Moreau, M Kaid…

文献索引：Villemin, Didier; Moreau, Bernard; Kaid, M'Hamed; Didi, Mohamed Amine Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 8 p. 1583 - 1586

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被引用次数: 14

摘要

Halide derivatives react with an excess of triethyl phosphite under microwave irradiation. In a mono-mode reactor, the reaction is complete within 10 min. Excesses of phosphites and alkyl halides are evaporated under vacuum. The mixture is hydrolyzed by a hydrobromic acid solution during 10 min under microwave irradiation, and the obtained diphosphonic acid is crystallized in water. ... We have used α,ω-dibromoalkanes for the preparation of alkane-α,ω- ...