Enhancement of antioxidant activity of p-alkylaminophenols by alkyl chain elongation

…, K Tamagawa, Y Kubo, T Fukui, H Wakabayashi…

文献索引：Takahashi, Noriko; Tamagawa, Kayoko; Kubo, Yoshinori; Fukui, Tetsuya; Wakabayashi, Hitoshi; Honda, Toshio Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 15 p. 3255 - 3260

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被引用次数: 20

摘要

The initial finding that the p-methylaminophenol (6) exhibited antioxidant activity led us to investigate whether the length of alkyl chains linked to the aminophenol residue might affect antioxidative activity. Therefore, we synthesized p-butylaminophenol (5), p- hexylaminophenol (4), p-octylaminophenol (3), and p-methoxybenzylaminophenol (7). All p- alkylaminophenols quenched α, α-diphenyl-β-picrylhydrazyl (DPPH) radicals, with 7 being ...