The novel class of a-metallo ketonea RCOCH2Tl% lyl (OCOCF& where R= phenyl, substituted phenyl, thienyl, pyridinyl, and tert-butyl have been synthesized and characterized by'H NMR and 13C NMR. These compounds serve aa anion equivalents in the TiC&- mediatd aldol condensation. Metal-metal exchange with iodosylbenzene or lead tetraacetate leads to a-nucleophilic substitution derived from the formal a-keto carbonium ...
