Tetrahedron: Asymmetry

Lipase-catalyzed separation of the enantiomers of 1-substituted-3-arylthio-2-propanols

M Wielechowska, J Plenkiewicz

文献索引：Wielechowska, Monika; Plenkiewicz, Jan Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1199 - 1205

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被引用次数: 10

摘要

Optically active (R)-and (S)-1-substituted-3-(arylthio) propan-2-ols have been prepared in the reaction of the appropriate 2-(arylthiomethyl) oxiranes with chloride and azide anions followed by a lipase-catalyzed transesterification. The effects of the enzyme preparation as