Potential photoaffinity labels for tubulin. synthesis and evaluation of diazocyclohexadienone and azide analogs of colchicine, combretastatin, and 3, 4, 5- …
JD Olszewski, M Marshalla, M Sabat…
文献索引：Olszewski; Marshalla; Sabat; Sundberg Journal of Organic Chemistry, 1994 , vol. 59, # 15 p. 4285 - 4296
Colchicine has a unique place in the study of antimi-totic substances which act by affecting the tubulin assembly-disassembly process.'Indeed, the colchicinebinding property of tubulin was the basis of its initial isolation. 2 Subsequently, many other naturally-occuning and synthetic compounds which bind at the “colchicine site” and inhibit tubulin assembly have been identified. One subset of these has in common the trimethoxybenzene ring found in ...
