Tetrahedron

Synthesis of heteroaryl ketones via tandem reaction of 1, 1-dibromoethenes

X Fan, Y He, X Zhang, S Guo, Y Wang

文献索引：Fan, Xuesen; He, Yan; Zhang, Xinying; Guo, Shenghai; Wang, Yangyang Tetrahedron, 2011 , vol. 67, # 34 p. 6369 - 6374

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被引用次数: 26

摘要

A novel method for the synthesis of heteroaryl ketones through one-pot tandem reaction of 1, 1-dibromoethenes with 2-amino (thio) phenols promoted by TBAF· 3H2O and RuCl3 (5%)/air was developed. This novel method includes several reactions in one-pot and utilizes economical yet efficient reagents to generate synthetically and biologically interesting heteroaryl ketones under mild conditions with good efficiency.