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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Synthesis of Pyridin-2 (1 H)-one Derivatives via Enamine Cyclization

…, V Bhawe, B Ghotekar, M Jachak…

文献索引：Jachak, Madhukar; Kriessmann, Ulrike; Mittelbach, Martin; Junek, Hans Monatshefte fuer Chemie, 1993 , vol. 124, p. 199 - 208

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被引用次数: 13

摘要

The nucleophilic vinylic substitution reaction of the aliphatic enaminone 3-dimethylamino-2- formyl acrylonitrile 1 with the nucleophiles malononitrile and ethyl cyanoacetate produced the two unusual reaction adducts 3a and 3b in good to moderate yield under milder reaction

2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)结构式

2-Propenenitril...

4-硝基苯肼结构式

~63%

1-(4-nitrophenyl)-1H-pyrazole-4-carbonitrile结构式

1-(4-nitropheny...

2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)结构式

2-Propenenitril...

对甲基苯肼结构式

对甲基苯肼

~80%

1-p-tolyl-1H-pyrazole-4-carbonitrile结构式

1-p-tolyl-1H-py...

3-氧代丙腈结构式

2,4,6-三溴苯胺结构式

2,4,6-三溴苯胺

~29%

3-anilinoprop-2-enenitrile结构式

3-anilinoprop-2...

2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)结构式

2-Propenenitril...

苯肼结构式

~79%

1-苯基-1H-吡唑-4-腈结构式

1-苯基-1H-吡唑-4-腈

2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)结构式

2-Propenenitril...

甲基肼结构式

~61%

1-甲基吡唑-4-甲腈结构式

1-甲基吡唑-4-甲腈

2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)结构式

2-Propenenitril...

~56%

4-氰基吡唑结构式

2-肼基乙醇结构式

3-氧代丙腈结构式

~61%

5-氨基-1-(2-羟乙基)吡唑结构式

5-氨基-1-(2-羟乙基)吡唑

Synthesis and antileishmanial activity of new 1-aryl-1H-pyra...

[Dos Santos, Mauricio S.; Gomes, Adriana O.; Bernardino, Alice M. R.; De Souza, Marcos C.; Khan, Misbahul A.; De Brito, Monique A.; Castro, Helena C.; Abreu, Paula A.; Rodrigues, Carlos R.; De Leo, Rosa M. M.; Leon, Leonor L.; Canto-Cavalheirr, Marilene M. Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 2 p. 352 - 358]

Synthesis and antileishmanial activity of new 1-aryl-1H-pyra...

[Dos Santos, Mauricio S.; Gomes, Adriana O.; Bernardino, Alice M. R.; De Souza, Marcos C.; Khan, Misbahul A.; De Brito, Monique A.; Castro, Helena C.; Abreu, Paula A.; Rodrigues, Carlos R.; De Leo, Rosa M. M.; Leon, Leonor L.; Canto-Cavalheirr, Marilene M. Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 2 p. 352 - 358]

Synthesis and antileishmanial activity of new 1-aryl-1H-pyra...

[Dos Santos, Mauricio S.; Gomes, Adriana O.; Bernardino, Alice M. R.; De Souza, Marcos C.; Khan, Misbahul A.; De Brito, Monique A.; Castro, Helena C.; Abreu, Paula A.; Rodrigues, Carlos R.; De Leo, Rosa M. M.; Leon, Leonor L.; Canto-Cavalheirr, Marilene M. Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 2 p. 352 - 358]