The Journal of organic chemistry

Molecular iodine-catalyzed facile procedure for N-Boc protection of amines

R Varala, S Nuvula, SR Adapa

文献索引：Varala, Ravi; Nuvula, Sreelatha; Adapa, Srinivas R. Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8283 - 8286

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被引用次数: 159

摘要

An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc) 2O in the presence of a catalytic amount of molecular iodine (10 mol%) under solvent-free conditions at ambient temperature is presented.