Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles

K Bahrami, MM Khodaei, F Naali

文献索引：Bahrami, Kiumars; Mehdi Khodaei; Naali, Fardin Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6835 - 6837

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被引用次数: 296

摘要

Compounds that exhibit the functionality of benzimidazole and benzothiazole have been extensively employed in the area of pharmaceuticals. 1–4 The high profile of biological applications of compounds with benzimidazole and benzothiazole structures has prompted extensive studies for their synthesis. Methods of benzimidazole synthesis include the condensation of 1, 2-phenylendiamines with carboxylic acids or their derivatives in the ...