Chinese Chemical Letters

Microwave-assisted convenient synthesis of N-arylpyrrolidines in water

HB Li, W Liang, L Liu, K Chen, Y Wu

文献索引：Li, Hong Bo; Liang, Wu; Liu, Lang; Chen, Kai; Wu, Yi Chinese Chemical Letters, 2011 , vol. 22, # 3 p. 276 - 279

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摘要

Pyrrolidines are common structural subunits present in natural and unnatural products [1]. Depending upon the substituents, pyrrolidines have been reported to possess a variety of important biological activities [2], including antibacterial, neuromodulatory, glycosidase inhibitory, and fungicidal activities. Among these, N-arylpyrrolidines, an important class of compounds, are prepared via alkylation of arylamines with glycol disulfonate in organic solvent for long times [3], using ...