Discovery of novel N-(5-(arylcarbonyl) thiazol-2-yl) amides and N-(5-(arylcarbonyl) thiophen-2-yl) amides as potent RORγt inhibitors

Y Wang, W Cai, G Zhang, T Yang, Q Liu…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 22, # 2 p. 692 - 702

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被引用次数: 22

摘要

... Bioorganic & Medicinal Chemistry. Volume 22, Issue 2, 15 January 2014, Pages 692–702. Cover image Cover image. ... On the basis of its in vitro activities, 6a was used as a chemical starting point for further optimization. 2.1. SAR. ...