2-[[[2-(2, 6-Dimethoxyphenoxy) ethyl] amino] methyl]-1, 4-benzoxathian: a new antagonist with high potency and selectivity towards. alpha. 1-adrenoreceptors

…, D Giardina, M Pigini, G Strappaghetti

文献索引：Melchiorre; Brasili; Giardina; Pigini; Strappaghetti Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1535 - 1536

全文：HTML全文

被引用次数: 51

摘要

Much evidence supports the view that the a-adrenoreceptor is not a homogeneous entity. In addition to the classical postsynaptic a-adrenoreceptor, called al, that initiates the response of the effector organ, there is a presynaptic a-adrenoreceptor, named az, that modulates neurotransmitter release by a feedback me~ hanism. l-~ However, this classification does not always hold true since a,-and a2-adrenoreceptors can be found in regions other than ...