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Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase

T Nittoli, K Curran, S Insaf, M DiGrandi…

文献索引:Journal of Medicinal Chemistry, , vol. 50, # 9 p. 2108 - 2116

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被引用次数: 52

摘要

... Journal of Medicinal Chemistry. ... 7. Despite a proliferation of pharmaceutical and academic research in the past decade, no specific antiviral agents are available for the treatment of HCV, and there remains an enormous unmet medical need for adequate therapeutic options. ...