The Journal of organic chemistry

Selective Synthesis of Either Isoindole-or Isoindoline-1-carboxylic Acid Esters by Pd (0)-Catalyzed Enolate Arylation

D Solé, O Serrano

文献索引：Sole, Daniel; Serrano, Olga Journal of Organic Chemistry, 2010 , vol. 75, # 18 p. 6267 - 6270

被引用次数: 25

摘要

Two efficient palladium-catalyzed intramolecular α-arylation reactions of α-amino acid esters have been developed that allow either 1-isoindolecarboxylic acid esters or the corresponding isoindolines to be selectively synthesized simply by a slight change of reaction conditions.

~10%

~15%

~5%

~29%

~59%

~93%

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