Medicinal Flowers. Part 29. Acylated Oleanane??Type Triterpene Bisdesmosides: Perennisaponins G, H, I, J, K, L, and M with Pancreatic Lipase Inhibitory Activity from …

T Morikawa, X Li, E Nishida, S Nakamura…

文献索引：Morikawa, Toshio; Li, Xuezheng; Nishida, Eriko; Nakamura, Seikou; Ninomiya, Kiyofumi; Matsuda, Hisashi; Oda, Yoshimi; Muraoka, Osamu; Yoshikawa, Masayuki Helvetica Chimica Acta, 2010 , vol. 93, # 3 p. 573 - 586

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被引用次数: 21

摘要

Abstract The MeOH extract from the flowers of Bellis perennis was found to show pancreatic- lipase inhibitory activity (IC 50 455 μg/ml). From the extract, seven new triterpene saponins named perennisaponins G (1; IC 50 163 μ M), H (2; 137 μ M), I (3; 147 μ M), J (4; 148 μ M), K (5; 223 μ M), L (6; 81.4 μ M), and M (7; 195 μ M) were isolated as pancreatic lipase inhibitors. The stereostructures of 1–7 were elucidated on the basis of chemical and ...