Green Chemistry

Synthesis of pyrazoles through catalyst-free cycloaddition of diazo compounds to alkynes

D Vuluga, J Legros, B Crousse, D Bonnet-Delpon

文献索引：Vuluga, Daniela; Legros, Julien; Crousse, Benoit; Bonnet-Delpon, Daniele Green Chemistry, 2009 , vol. 11, # 2 p. 156 - 159

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被引用次数: 41

摘要

The synthesis of pyrazoles via1, 3-dipolar cycloaddition of diazo compounds to alkynes proceeds easily by heating. With α-diazocarbonyl substrates the reactions are conducted under solvent-free conditions affording the pyrazole products in high yields without any work up or purification.