Synthesis and immunological characterization of modified hyaluronic acid hexasaccharide conjugates

G Gu, PJP Adabala, MG Szczepina…

文献索引：Journal of Organic Chemistry, , vol. 78, # 16 p. 8004 - 8019

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被引用次数: 6

摘要

... The Journal of Organic Chemistry. ... First, coupling of the acceptor 5 and trichoroacetimidate 8 in dichloromethane with TMSOTf as promoter afforded the β-(1 → 4)-linked disaccharide 12 in 81% yield (Scheme 5). The chemical shifts of H-1′ (δ 5.49 ppm, J 1′,2′ 8.2 Hz) and ...