Synthesis and biological evaluation of new 4β-anilino-4′-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents

L Wang, F Yang, X Yang, X Guan, C Hu, T Liu…

文献索引：European Journal of Medicinal Chemistry, , vol. 46, # 1 p. 285 - 296

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被引用次数: 16

摘要

... European Journal of Medicinal Chemistry. ... and poor water-solubility, which block their further application [6]. Thus, it is valuable for medicinal chemists to overcome drug ... The obtained aryl amides 12a–j were further reduced to the corresponding amines 14a–m first by borane and ...