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Chemical and pharmaceutical bulletin

Studies on 4 (1H)-quinazolinones. III. Some derivatizations of 2-ethoxycarbonylalkyl-1-substituted-4 (1H)-quinazolinones.

尾崎建一，山田義久，大稲豊生

文献索引：Ozaki, Ken-Ichi; Yamada, Yoshihisa; Oine, Toyonari Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2234 - 2243

全文：HTML全文

被引用次数: 19

摘要

... III.” Some Derivatizations of 2-Ethoxycarbonylalkyl-l-substituted-4(1H)-quinazolinones KEN-ICHI OZAKI, YOSHIHISA YAMADA,* and TOYONARI OINE Research Laboratory ... dimethylformamide gave 3-ethoxycarbonyl-4—hydroxy-lH—pyrido[l,2-a]quinazolin-6(2H)— one (27 ...

环氧乙烷结构式

Benzenecarboximidic acid, 2-amino- (9CI)结构式

Benzenecarboxim...

~23%

2-(2-hydroxyethylamino)benzamide结构式

2-(2-hydroxyeth...

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

~68%

1-methyl-2-(2H-tetrazol-5-yl)quinazolin-4-one结构式

1-methyl-2-(2H-...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-methyl-2-(2H-tetrazol-5-yl)quinazolin-4-one结构式

1-methyl-2-(2H-...

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~%

1-methyl-2-(2H-tetrazol-5-yl)quinazolin-4-one结构式

1-methyl-2-(2H-...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

1-methyl-2-(2H-tetrazol-5-yl)quinazolin-4-one结构式

1-methyl-2-(2H-...

3-ethoxycarbonyl-3-methyl-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one结构式

3-ethoxycarbony...

~33%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

Benzenecarboximidic acid, 2-amino- (9CI)结构式

Benzenecarboxim...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

2-(2-hydroxyethylamino)benzamide结构式

2-(2-hydroxyeth...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

2-(2-chloroethylamino)benzamide结构式

2-(2-chloroethy...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

1-(2-chloroethyl)-2-(1-ethoxycarbonylethyl)-4(1H)-quinazolinone结构式

1-(2-chloroethy...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

2-(1-ethoxycarbonylethyl)-1-(2-hydroxyethyl)-4(1H)-quinazolinone结构式

2-(1-ethoxycarb...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

1-(2-(2-(1-ethoxy-1-oxopropan-2-yl)-4-oxoquinazolin-1(4H)-yl)ethyl) 3-ethyl 2-methylmalonate结构式

1-(2-(2-(1-etho...

~%

3-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]quinazolin-5-one结构式

3-methyl-2,3-di...

4-ethoxycarbonyl-4-methyl-1,2,3,4-tetrahydro-6H-pyrido[1,2-a]quinazolin-6-one结构式

4-ethoxycarbony...

~54%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

2-(3-hydroxypropylamino)benzamide结构式

2-(3-hydroxypro...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

2-((3-chloropropyl)amino)benzamide结构式

2-((3-chloropro...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

2-(2-methoxycarbonylethylamino)benzamide结构式

2-(2-methoxycar...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

methyl 3-(2,4-dioxo-3,1-benzoxazin-1-yl)propanoate结构式

methyl 3-(2,4-d...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

ethyl 2-(1-(3-chloropropyl)-4-oxo-1,4-dihydroquinazolin-2-yl)propanoate结构式

ethyl 2-(1-(3-c...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

2-(1-ethoxycarbonylethyl)-1-(3-hydroxypropyl)-4(1H)-quinazolinone结构式

2-(1-ethoxycarb...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

1-(3-(2-(1-ethoxy-1-oxopropan-2-yl)-4-oxoquinazolin-1(4H)-yl)propyl) 3-ethyl 2-methylmalonate结构式

1-(3-(2-(1-etho...

~%

4-methyl-1,2,3,4-tetrahydropyrido[1,2-a]quinazolin-6-one结构式

4-methyl-1,2,3,...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

草酰氯单乙酯结构式

草酰氯单乙酯

~91%

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

草酰氯单乙酯结构式

草酰氯单乙酯

ethyl 4-(2-carbamoylanilino)butanoate结构式

ethyl 4-(2-carb...

~84%

ethyl 1-(4-ethoxy-4-oxobutyl)-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-(4-etho...

ethyl 4-(2,4-dioxo-3,1-benzoxazin-1-yl)butanoate结构式

ethyl 4-(2,4-di...

~%

ethyl 1-(4-ethoxy-4-oxobutyl)-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-(4-etho...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~92%

1-methyl-4-oxoquinazoline-2-carboxylic acid结构式

1-methyl-4-oxoq...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-methyl-4-oxoquinazoline-2-carboxylic acid结构式

1-methyl-4-oxoq...

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

~62%

2-amino-1-methylquinazolin-4-one结构式

2-amino-1-methy...

N-hydroxy-1-methyl-4-oxoquinazoline-2-carboxamide结构式

N-hydroxy-1-met...

~62%

2-amino-1-methylquinazolin-4-one结构式

2-amino-1-methy...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

2-amino-1-methylquinazolin-4-one结构式

2-amino-1-methy...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

2-amino-1-methylquinazolin-4-one结构式

2-amino-1-methy...

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~%

2-amino-1-methylquinazolin-4-one结构式

2-amino-1-methy...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~63%

N-hydroxy-1-methyl-4-oxoquinazoline-2-carboxamide结构式

N-hydroxy-1-met...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

N-hydroxy-1-methyl-4-oxoquinazoline-2-carboxamide结构式

N-hydroxy-1-met...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~99%

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

氨基甲烷结构式

~61%

1-methyl-2-(methylamino)quinazolin-4-one结构式

1-methyl-2-(met...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-methyl-2-(methylamino)quinazolin-4-one结构式

1-methyl-2-(met...

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~%

1-methyl-2-(methylamino)quinazolin-4-one结构式

1-methyl-2-(met...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

1-methyl-2-(methylamino)quinazolin-4-one结构式

1-methyl-2-(met...

1-methyl-4-oxoquinazoline-2-carboxylic acid结构式

1-methyl-4-oxoq...

~91%

1-甲基喹唑啉-4(1H)-酮结构式

1-甲基喹唑啉-4(1H)-酮

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-甲基喹唑啉-4(1H)-酮结构式

1-甲基喹唑啉-4(1H)-酮

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

1-甲基喹唑啉-4(1H)-酮结构式

1-甲基喹唑啉-4(1H)-酮

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~50%

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

3-巯基丙酸结构式

~46%

3-(1-methyl-4-oxoquinazolin-2-yl)sulfanylpropanoic acid结构式

3-(1-methyl-4-o...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

3-(1-methyl-4-oxoquinazolin-2-yl)sulfanylpropanoic acid结构式

3-(1-methyl-4-o...

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~%

3-(1-methyl-4-oxoquinazolin-2-yl)sulfanylpropanoic acid结构式

3-(1-methyl-4-o...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

3-(1-methyl-4-oxoquinazolin-2-yl)sulfanylpropanoic acid结构式

3-(1-methyl-4-o...

ethyl 4-(2,4-dioxo-3,1-benzoxazin-1-yl)butanoate结构式

ethyl 4-(2,4-di...

~54%

ethyl 4-(2-carbamoylanilino)butanoate结构式

ethyl 4-(2-carb...

羟基乙酸结构式

1-methyl-4-oxoquinazoline-2-carbonitrile结构式

1-methyl-4-oxoq...

~41%

2-(1-methyl-4-oxoquinazolin-2-yl)oxyacetic acid结构式

2-(1-methyl-4-o...

2-(甲基氨基)苯甲酰胺结构式

2-(甲基氨基)苯甲酰胺

~%

2-(1-methyl-4-oxoquinazolin-2-yl)oxyacetic acid结构式

2-(1-methyl-4-o...

1-methyl-4-oxoquinazoline-2-carboxamide结构式

1-methyl-4-oxoq...

~%

2-(1-methyl-4-oxoquinazolin-2-yl)oxyacetic acid结构式

2-(1-methyl-4-o...

ethyl 1-methyl-4-oxoquinazoline-2-carboxylate结构式

ethyl 1-methyl-...

~%

2-(1-methyl-4-oxoquinazolin-2-yl)oxyacetic acid结构式

2-(1-methyl-4-o...

2-(2-hydroxyethylamino)benzamide结构式

2-(2-hydroxyeth...

~49%

2-(2-chloroethylamino)benzamide结构式

2-(2-chloroethy...

Benzenecarboximidic acid, 2-amino- (9CI)结构式

Benzenecarboxim...

~%

2-(2-chloroethylamino)benzamide结构式

2-(2-chloroethy...

2-(2-methoxycarbonylethylamino)benzamide结构式

2-(2-methoxycar...

~66%

2-(3-hydroxypropylamino)benzamide结构式

2-(3-hydroxypro...

methyl 3-(2,4-dioxo-3,1-benzoxazin-1-yl)propanoate结构式

methyl 3-(2,4-d...

~%

2-(3-hydroxypropylamino)benzamide结构式

2-(3-hydroxypro...