Synthesis

A fast synthesis of 2-acylamino-2-alkenoic acids

PK Tripathy, AK Mukerjee

文献索引：Tripathy, Pradeep K.; Mukerjee, Arya K. Synthesis, 1984 , # 5 p. 418 - 422

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被引用次数: 14

摘要

8 6"; GH cohol used '. The ethyl esters may be obtained in much better b CH ON _© _ yield by treating compounds 5 with ethanol in the presence of '1 H a catalytic amount of potassium hydroxide. This result is c© _ H CM obviously due to the generation of ethoxide ion which brings about cleavage of the 1, 5-bond of 5. In order to ascertain the cl© _ H CH3 effectiveness of the base-catalysed alcoholysis of 5, methano-lysis of a few compounds 5 ...